ceesdekker.net - An Overview
ceesdekker.net - An Overview
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Spatial framework facilitates cooperation inside of a social Predicament: empirical proof from the bacterial Local community
It had been only during the nineties nevertheless, when nanotechnology had Highly developed into a amount the place one molecules could possibly be manipulated, that the very first experimental products began to seem.
‘It was simply a make any difference of buying up a e book on cell biology and starting to read. I'd come from a globe of extremely-substantial vacuums, cryostats and quantum phenomena, and now I used to be working at home temperature with molecular biology kits.
Sculpting nano-electrodes using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Our investigate ranges through the biophysics of DNA to synthetic cells and further than. Remember to have a look underneath with the spectrum of our present jobs.
We use nanofabricated microfluidic structures to sample spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this evaluate the fundamental job of spatial confinement with the molecular and cellular amount. Our assignments contain the subsequent:
Dynamic ParB–DNA interactions initiate and keep a partition condensate for bacterial chromosome segregation
‘Sure, I have an understanding of folks were being stunned at some time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to admit that it experienced become a bit bored, I didn’t study A lot any more. The sphere went a lot more into the applying side, how you may combine nanotubes into Digital circuits.
But carbon nanotubes have remained a exploration matter of sizeable desire to lots of. In fact, the outlook on working with carbon nanotubes to develop functional products, in regions for example radio-frequency electronics, digital electronics and flexible electronics, continues to be shiny.
Considering that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from scientific tests of DNA loop extrusion and supercoiling to DNA translocation by means of nanopores. More a short while ago his investigation ceesdekker has focused on learning chromatin composition and cell division with microorganisms on chip, whilst he can also be trying to finally Create artificial cells from The underside up.
Cees Dekker is Distinguished College Professor at TU Delft. Experienced to be a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes in the nineteen nineties. Since 2000, he moved to one-molecule biophysics and nanobiology. His current research concentrates on (i) nanopores for protein sequencing; (ii) chromosome composition, especially SMC motor protein; and (iii) developing a residing synthetic cell from lifeless molecules. Dekker is an elected member of the KNAW and fellow into the APS and the IOP.
2008, 1st observation of protein-coated DNA translocation by way of nanopores; solved the origin on the electrophoretic power on DNA in nanopores; identified a major velocity boost of microtubules in electrical fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of noise in carbon nanotubes in liquid
2013, controlled shaping of Stay bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations during the handedness of histone tetrasomes